Dr. Larson was invited to respond to Dr. Nyström's comments

Authors reply to Dr. Kawada's comments.

We thank Dr. Kawada for his insightful comments [1] on our study [2], which highlights the importance of the C-reactive protein (CRP) concentration as a significant risk marker for metabolic syndrome (MetS). Dr. Kawada argued that stratified analyses by gender for the association between CRP concentrations and MetS should be performed in our study, given that there were gender differences in th...

Authors' Reply to Comments from Dr. Guan

To the Editor. We thank Dr. Guan for his interest in our recent article [1]. He has raised some comments regarding possible potential of MT and zinc as therapeutic tools for inflammatory diseases. As he mentions, simply inducing and/or enhancing metallothionein (MT) is harmful, particularly in physiological condition. We want to emphasize that for severe (lethal) inflammatory conditions such as...

Rebuttal Comments from Dr. Dunn and Dr. Wechsler

I ntroduction: In recent years a number of emerging new therapies have become available for the treatment of severe asthma among which bronchial ther-moplasty is the only nonpharmacologic intervention that has been approved by the United States Food and Drug Administration in 2010. 1 Although bronchial thermoplasty has great promise for the patient with severe asthma and is now within the thera...

’ Reply to Comments Made by Reviewer Dr . Garratt

This is dedicated to our former chairman Dr. Mahmoud Rohani